CALL FOR PAPERS Epigenetics and Epigenomics Genome-wide analysis of the rat colon reveals proximal-distal differences in histone modifications and proto-oncogene expression
نویسندگان
چکیده
Karen Triff, Kranti Konganti, Sally Gaddis, Beiyan Zhou, Ivan Ivanov, and Robert S. Chapkin Program in Integrative Nutrition & Complex Diseases, Texas A&M University, College Station, Texas; Department of Nutrition & Food Science, Texas A&M University, College Station, Texas; Department of Veterinary Physiology & Pharmacology, Texas A&M University, College Station, Texas; Center for Translational Environmental Health Research, Texas A&M University, College Station, Texas; Department of Biology, Texas A&M University, College Station, Texas; and Whole Systems Genomics Initiative, Texas A&M University, College Station, Texas
منابع مشابه
Genome-wide analysis of the rat colon reveals proximal-distal differences in histone modifications and proto-oncogene expression.
Since disease susceptibility of the intestine exhibits an anatomical bias, we propose that the chromatin landscape, especially the site-specific epigenetic differences in histone modification patterns throughout the colonic longitudinal axis, contributes to the differential incidence of site-specific pathology. To test this hypothesis, we assessed the chromatin structure associated with gene ex...
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